Layilin Antikörper (AA 22-235)

Produktnummer ABIN5775959

Dieser Anti-Layilin Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von Layilin in WB und ELISA. Geeignet für Human.

Kurzübersicht für Layilin Antikörper (AA 22-235) (ABIN5775959)

Target: Layilin (LAYN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Layilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: AT18E10

Produktdetails anti-Layilin Antikörper

Bindungsspezifität: AA 22-235

Verwendungszweck: Human Layilin/LAYN antibody

Aufreinigung: Purified

Immunogen: Recombinant human LAYN (22-235aa) purified from E. coli

Isotyp: IgG1 kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu Layilin

Target: Layilin (LAYN)

Andere Bezeichnung: Layilin/LAYN

Hintergrund: Layilin is a widely expressed integral membrane hyaluronan receptor and a transmembrane protein with homology to C-type lectins. This protein interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. The carboxy-terminal domain of layilin is capable of binding to the amino-terminal domain of radixin. An interdomain interaction between the amino- and the carboxy-terminal domains of radixin inhibits its ability to bind to layilin. Layilin plays an important role in cell adhesion and motility. It is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layilin acts as a membrane-binding site for talin in the peripheral ruffles, and it may play a role in the migration of cells to a wound site.

NCBI Accession: NP_001245319